CCNO

Across TCGA patient cohorts, CCNO protein abundance is significantly associated with the RNA expression of many other genes, with 949 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNO-associated genes across cancer lineages are POLR2F, TSPO, and ACR. Each is linked with CCNO in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNO-to-partner and partner-to-CCNO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNO versus POLR2F in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNO→partner) and Y-score (partner→CCNO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR2F →	+0.698	+0.993	<.001	.001	3	1
UCEC	TSPO →	+1.769	+0.990	.007	.002	3	1
UCEC	ACR →	-0.374	-0.971	.003	<.001	3	1
UCEC	PRMT5 →	+0.545	+0.836	.004	.002	3	1
UCEC	PSMB5 →	+1.293	+0.973	<.001	.001	3	1
UCEC	IFT52 →	+0.481	+0.876	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 949 associations by consensus.

CCNO vs POLR2F — UCEC

Explore this scatter interactively →