CCNO

Across TCGA cell cohorts, CCNO RNA expression is significantly associated with the go_rna of many other GO terms, with 2,700 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNO-associated GO terms across cancer lineages are Nucleotide biosynthetic process, Xenophagy, and Actomyosin contractile ring organization. Each is linked with CCNO in more than 6 cancer types. Because this analysis shows association rather than direction, both CCNO-to-partner and partner-to-CCNO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide biosynthetic process grouped by CCNO-low versus CCNO-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNO→partner) and Y-score (partner→CCNO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleotide biosynthetic process →	+0.074	+1.164	.007	.002	3	6
CNS	Xenophagy →	+0.112	+0.831	<.001	.001	3	6
SOFT_TISSUE	Actomyosin contractile ring organization →	+0.117	+1.203	.002	.001	3	6
URINARY_TRACT	Metanephric proximal tubule development →	+0.247	+1.382	.001	.001	3	6
BONE	Transcription pausing by RNA polymerase II →	+0.143	+0.945	<.001	.001	3	6
OESOPHAGUS	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.048	+0.713	.003	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,700 associations by consensus.

Nucleotide biosynthetic process by CCNO expression — BONE

Explore this box plot interactively →