CCNL1

Across TCGA pan-cancer cohorts, CCNL1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCNL1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CCNL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCNL1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where CCNL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.900	0.329	.019	7	view →
CCRCC	DFS	Tertile	All	1.000	0.341	.016	7	view →
HNSC	DFS	Tertile	All	0.991	0.906	.020	3	view →
GBM	OS	Quartile	All	0.802	0.884	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCNL1–PDAC (DFS)

Open the PDAC breakdown →