CCNK

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNK mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNK-associated genes across cancer lineages are Neutrophils, MEP, and Endothelial cells. Each is linked with CCNK in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNK-to-partner and partner-to-CCNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by CCNK-low versus CCNK-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNK→partner) and Y-score (partner→CCNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNeutrophils →+0.014+1.681.003.04933
UCECMEP →+0.045+3.032.001.01821
UCECEndothelial cells →-0.043-3.416.023.00511
UCECmv Endothelial cells →-0.026-2.311.026.03611
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Neutrophils by CCNK expression — UCEC

Box plot of Neutrophils in CCNK-low vs CCNK-high samples in UCEC.

Explore this box plot interactively →

Exploration