CCNK

Across TCGA cell cohorts, CCNK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,486 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNK-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of cell cycle, and Negative regulation of G2/M transition of mitotic cell cycle. Each is linked with CCNK in more than 12 cancer types. Because this analysis shows association rather than direction, both CCNK-to-partner and partner-to-CCNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by CCNK-low versus CCNK-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNK→partner) and Y-score (partner→CCNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Epigenetic regulation of gene expression →	+0.053	+0.840	<.001	<.001	3	13
KIDNEY	Positive regulation of cell cycle →	+0.062	+1.044	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of G2/M transition of mitotic cell cycle →	+0.060	+0.871	<.001	.001	3	12
BLOOD_Lymphoma	Negative regulation of cell cycle G2/M phase transition →	+0.059	+0.871	<.001	.001	3	12
CNS	Positive regulation of spindle checkpoint →	+0.094	+0.612	.001	.001	3	12
CNS	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.094	+0.612	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,486 associations by consensus.

Epigenetic regulation of gene expression by CCNK expression — BLOOD_Lymphoma

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