CCNK

Across TCGA cell cohorts, CCNK mutation is significantly associated with the mutation status of many other genes, with 3,314 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNK-associated genes across cancer lineages are MOSPD3, TARDBP, and SPOP. Each is linked with CCNK in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNK-to-partner and partner-to-CCNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOSPD3 grouped by CCNK-low versus CCNK-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNK→partner) and Y-score (partner→CCNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MOSPD3 →	+5.584	+5.014	.003	.003	1	3
BLOOD_Lymphoma	TARDBP →	+5.584	+5.014	.003	.003	1	3
BLOOD_Lymphoma	SPOP →	+4.584	+4.584	.007	.007	1	3
BLOOD_Lymphoma	DOCK4 →	+4.169	+5.316	<.001	<.001	1	3
BLOOD_Lymphoma	CDK8 →	+5.584	+5.014	.003	.003	1	3
UPPER_AERODIGESTIVE_TRACT	TPP2 →	+4.954	+4.392	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,314 associations by consensus.

MOSPD3 by CCNK expression — BLOOD_Lymphoma

Explore this box plot interactively →