CCNJ

Across TCGA patient cohorts, CCNJ mutation is significantly associated with the RNA expression of many other genes, with 2,984 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNJ-associated genes across cancer lineages are RNA5SP412, RNU6-222P, and RNA5SP146. Each is linked with CCNJ in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNJ-to-partner and partner-to-CCNJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by CCNJ-low versus CCNJ-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNJ→partner) and Y-score (partner→CCNJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.627	+1.774	<.001	.009	3	2
UCEC	RNU6-222P →	+0.403	+2.031	<.001	.003	3	2
UCEC	RNA5SP146 →	+0.275	+2.022	<.001	.006	3	2
UCEC	RNA5SP413 →	+1.020	+1.639	<.001	.008	3	2
SKCM	KRTAP23-1 →	+0.105	+4.614	<.001	.006	3	2
SKCM	E2F6P1 →	+0.052	+5.179	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,984 associations by consensus.

RNA5SP412 by CCNJ expression — UCEC

Explore this box plot interactively →