CCNJ

Across TCGA cell cohorts, CCNJ mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CCNJ-associated genes across cancer lineages are UTF1, ENTHD1, and C1orf87. Each is linked with CCNJ in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNJ-to-partner and partner-to-CCNJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTF1 grouped by CCNJ-low versus CCNJ-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNJ→partner) and Y-score (partner→CCNJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	UTF1 →	+0.226	+5.357	<.001	.003	3	2
LARGE_INTESTINE	ENTHD1 →	+0.026	+4.139	.009	.007	3	1
BLOOD_Lymphoma	C1orf87 →	+0.021	+4.867	.008	.009	3	1
BLOOD_Lymphoma	ART5 →	+0.122	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DEFB125 →	+0.019	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	DYNAP →	+0.102	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

UTF1 by CCNJ expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →