CCNI

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNI protein abundance is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCNI-associated genes across cancer lineages are MOB3B, UBE2M, and MED18. Each is linked with CCNI in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNI-to-partner and partner-to-CCNI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNI versus MOB3B in GBM, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNI→partner) and Y-score (partner→CCNI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMOB3B →-1.993-0.505.001<.00131
GBMUBE2M →+0.606+0.540.003.00831
GBMMED18 →+0.318+0.409.005.00331
GBMCEMIP2 →-1.163-0.465.006.00531
GBMFGD4 →-0.758-0.432.004.00131
GBMSNRPF →+0.436+0.458.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

CCNI vs MOB3B — GBM

Per-sample scatter of CCNI vs MOB3B in GBM (Pearson r = -0.70).

Explore this scatter interactively →

Exploration