CCNI

Across TCGA pan-cancer cohorts, CCNI RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CCNI’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CCNI RNA is repressed in tumor relative to normal tissue. In most cancer types CCNI is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.

BLCA, UCEC, and CHOL are the cancer types where CCNI tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCNI RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	−0.690	.003	8	view →
UCEC	All	All	−0.979	<.001	6	view →
CHOL	All	All	+1.443	<.001	3	view →
THCA	All	All	−0.387	<.001	3	view →
LUSC	All	III,IV	−0.631	.020	1	view →
KIRP	Male	All	−0.381	.036	1	view →
KIRC	All	All	+0.182	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CCNI–BLCA

Open the BLCA breakdown →