CCNI

Across TCGA cell cohorts, CCNI mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CCNI-associated genes across cancer lineages are MYF5, CDY2A, and GSTA5. Each is linked with CCNI in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNI-to-partner and partner-to-CCNI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by CCNI-low versus CCNI-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNI→partner) and Y-score (partner→CCNI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MYF5 →	+0.749	+5.321	<.001	.005	3	1
CNS	CDY2A →	+0.006	+5.321	.004	.005	3	1
CNS	GSTA5 →	+0.044	+4.981	<.001	.008	3	1
CNS	DPRX →	+0.064	+5.321	<.001	.005	3	1
STOMACH	GPR33 →	+0.027	+4.129	<.001	.007	3	1
STOMACH	USP17L17 →	+0.010	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MYF5 by CCNI expression — CNS

Explore this box plot interactively →