CCNH

Across TCGA patient cohorts, CCNH protein abundance is significantly associated with the protein abundance of many other proteins, with 24,260 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCNH-associated proteins across cancer lineages are CDK7, SNRPD2, and SUPT16H. Each is linked with CCNH in more than 8 cancer types. Because this analysis shows association rather than direction, both CCNH-to-partner and partner-to-CCNH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNH versus CDK7 in GBM, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNH→partner) and Y-score (partner→CCNH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDK7 →	+0.344	+0.361	<.001	<.001	3	9
GBM	SNRPD2 →	+0.283	+0.266	<.001	<.001	3	8
GBM	SUPT16H →	+0.634	+0.337	<.001	<.001	3	8
LSCC	UTP15 →	+0.355	+0.241	<.001	<.001	3	8
GBM	CPSF3 →	+0.251	+0.240	<.001	<.001	3	8
GBM	DDX46 →	+0.295	+0.239	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,260 associations by consensus.

CCNH vs CDK7 — GBM

Explore this scatter interactively →