CCNF

Across TCGA cell cohorts, CCNF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,035 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNF-associated GO terms across cancer lineages are Mitotic chromosome condensation, Sister chromatid segregation, and Regulation of chromosome condensation. Each is linked with CCNF in more than 19 cancer types. Because this analysis shows association rather than direction, both CCNF-to-partner and partner-to-CCNF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by CCNF-low versus CCNF-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNF→partner) and Y-score (partner→CCNF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic chromosome condensation →	+0.164	+1.021	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Sister chromatid segregation →	+0.122	+1.295	.001	<.001	3	20
OESOPHAGUS	Regulation of chromosome condensation →	+0.236	+0.917	.001	.003	3	20
OESOPHAGUS	DNA strand elongation involved in DNA replication →	+0.218	+1.049	<.001	<.001	3	20
BONE	Chromosome segregation →	+0.163	+1.769	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid segregation →	+0.126	+1.295	.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,035 associations by consensus.

Mitotic chromosome condensation by CCNF expression — BREAST

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