CCNE2

Across TCGA patient cohorts, CCNE2 mutation is significantly associated with the RNA expression of many other genes, with 344 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNE2-associated genes across cancer lineages are C2orf69P4, MIR3159, and RN7SKP144. Each is linked with CCNE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNE2-to-partner and partner-to-CCNE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2orf69P4 grouped by CCNE2-low versus CCNE2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNE2→partner) and Y-score (partner→CCNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C2orf69P4 →	+0.084	+7.741	<.001	.009	3	2
HNSC	MIR3159 →	+0.627	+5.368	<.001	.005	3	2
SKCM	RN7SKP144 →	+0.263	+7.485	<.001	<.001	3	2
UCEC	TRAJ21 →	+0.422	+2.503	.007	.004	3	2
CESC	RN7SL150P →	+0.153	+5.010	<.001	.009	3	1
CESC	RN7SL446P →	+0.136	+5.306	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 344 associations by consensus.

C2orf69P4 by CCNE2 expression — COAD

Explore this box plot interactively →