CCNE2

Across TCGA pan-cancer cohorts, CCNE2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CCNE2 data layer compared with 5 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher CCNE2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CCNE2 expression acts as an unfavorable survival marker, although some lineages such as UCS and THYM show a favorable association.

MESO, KIRP, and ACC are the cancer types where CCNE2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.413	0.660	<.001	129	view →
KIRP	OS	Median	All	0.579	0.786	<.001	114	view →
ACC	DFS	Tertile	All	0.467	0.847	<.001	108	view →
KICH	DFS	Median	II,III,IV	0.655	1.000	<.001	101	view →
UVM	DFS	Tertile	II,III,IV	0.317	0.882	<.001	88	view →
LIHC	DFS	Median	All	0.463	0.618	<.001	69	view →
KIRC	DFS	Quartile	II,III,IV	0.355	0.689	.001	45	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
LGG	OS	Tertile	All	0.816	0.961	<.001	27	view →
ESCA	OS	Median	All	0.466	1.000	.016	21	view →
SARC	OS	Median	All	0.429	0.755	.001	15	view →
SCLC	OS	Median	All	0.505	0.928	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CCNE2–MESO (OS)

Open the MESO breakdown →