CCNE2

Across TCGA cell cohorts, CCNE2 mutation is significantly associated with the drug of many other genes, with 40 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNE2-associated genes across cancer lineages are Mirin, Bromosporine, and SGC-CBP30. Each is linked with CCNE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNE2-to-partner and partner-to-CCNE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by CCNE2-low versus CCNE2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNE2→partner) and Y-score (partner→CCNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.432	+2.646	.022	.047	3	1
LARGE_INTESTINE	Bromosporine →	+0.448	+2.649	.008	.046	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.312	+2.649	.027	.046	3	1
LARGE_INTESTINE	RVX-208 →	+0.398	+2.646	.009	.047	3	1
LARGE_INTESTINE	PAK_5339 →	+0.373	+2.678	.011	.037	3	1
LARGE_INTESTINE	LMB_AB3 →	+0.360	+2.649	.044	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Mirin by CCNE2 expression — LARGE_INTESTINE

Explore this box plot interactively →