CCND3

Across TCGA patient cohorts, CCND3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,339 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CCND3-associated genes across cancer lineages are SOS2, PPM1A, and HIF1A. Each is linked with CCND3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCND3-to-partner and partner-to-CCND3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCND3 versus SOS2 in LSCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND3→partner) and Y-score (partner→CCND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SOS2 →	-0.466	-0.518	.008	.003	3	1
LSCC	PPM1A →	-0.282	-0.328	.006	.002	3	1
LSCC	HIF1A →	-0.441	-0.461	.007	<.001	3	1
LSCC	ZC3H14 →	-0.287	-0.397	.002	<.001	3	1
LSCC	RPS6KA5 →	-0.517	-0.362	<.001	<.001	3	1
LSCC	PPP4R3A →	-0.316	-0.354	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,339 associations by consensus.

CCND3 vs SOS2 — LSCC

Explore this scatter interactively →