CCND3

Across TCGA cell cohorts, CCND3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,294 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCND3-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Negative regulation of cilium assembly, and Tissue homeostasis. Each is linked with CCND3 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCND3-to-partner and partner-to-CCND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by CCND3-low versus CCND3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND3→partner) and Y-score (partner→CCND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Phosphatidylinositol biosynthetic process →	+0.058	+0.852	.001	.005	3	9
LIVER	Negative regulation of cilium assembly →	+0.069	+1.696	<.001	.001	3	8
LARGE_INTESTINE	Tissue homeostasis →	-0.047	-0.813	.005	.005	2	9
BLOOD_Leukemia	Signal transduction in response to DNA damage →	+0.032	+1.183	<.001	<.001	3	8
LARGE_INTESTINE	Anatomical structure homeostasis →	-0.047	-0.813	.005	.005	2	9
BONE	Negative regulation of t-circle formation →	+0.113	+0.823	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,294 associations by consensus.

Phosphatidylinositol biosynthetic process by CCND3 expression — SKIN

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