CCND3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCND3 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCND3-associated genes across cancer lineages are GRAP, MAG, and TMSB4Y. Each is linked with CCND3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCND3-to-partner and partner-to-CCND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRAP grouped by CCND3-low versus CCND3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND3→partner) and Y-score (partner→CCND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaGRAP →+2.793+3.070<.001.00832
BLOOD_LymphomaMAG →+1.012+3.655<.001<.00131
BLOOD_LymphomaTMSB4Y →+0.806+3.509<.001.00231
BLOOD_LymphomaGPER1 →+2.342+3.070<.001.00831
BLOOD_LymphomaSLITRK5 →+0.642+2.392.001.00731
BLOOD_LymphomaBTNL9 →+3.142+3.243<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

GRAP by CCND3 expression — BLOOD_Lymphoma

Box plot of GRAP in CCND3-low vs CCND3-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration