CCNB3

Across TCGA patient cohorts, CCNB3 mutation is significantly associated with the RNA expression of many other genes, with 5,723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNB3-associated genes across cancer lineages are LINC02210, MAP6D1, and MAK16. Each is linked with CCNB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCNB3-to-partner and partner-to-CCNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02210 grouped by CCNB3-low versus CCNB3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB3→partner) and Y-score (partner→CCNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02210 →	+0.394	+2.268	.001	.005	3	5
LUAD	MAP6D1 →	+0.479	+2.924	.002	<.001	3	4
UCEC	MAK16 →	+0.385	+1.347	<.001	.005	3	4
LUAD	SNRPD3 →	+0.389	+1.772	<.001	.004	3	4
UCEC	XPNPEP1 →	+0.321	+1.496	<.001	.001	3	4
LUAD	NEIL3 →	+0.939	+2.819	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,723 associations by consensus.

LINC02210 by CCNB3 expression — LUAD

Explore this box plot interactively →