CCNB3

Across TCGA cell cohorts, CCNB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,477 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNB3-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and DNA replication. Each is linked with CCNB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCNB3-to-partner and partner-to-CCNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CCNB3-low versus CCNB3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB3→partner) and Y-score (partner→CCNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.089	+1.084	<.001	.001	3	8
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.086	+1.028	<.001	.002	3	8
LARGE_INTESTINE	DNA replication →	+0.084	+0.605	<.001	<.001	3	7
BLOOD_Lymphoma	Heterochromatin formation →	+0.057	+0.433	<.001	.006	3	7
BREAST	Cytoplasmic translation →	+0.073	+1.315	.001	<.001	3	7
BLOOD_Leukemia	Chromosomal DNA methylation maintenance following DNA replication →	+0.082	+0.459	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,477 associations by consensus.

Negative regulation of myoblast fusion by CCNB3 expression — BREAST

Explore this box plot interactively →