CCNB3

Across TCGA cell cohorts, CCNB3 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCNB3-associated genes across cancer lineages are H1-8, RXFP3, and OR2M5. Each is linked with CCNB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNB3-to-partner and partner-to-CCNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H1-8 grouped by CCNB3-low versus CCNB3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB3→partner) and Y-score (partner→CCNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	H1-8 →	+0.023	+3.472	<.001	.004	3	2
OESOPHAGUS	RXFP3 →	+0.006	+4.906	<.001	.006	3	1
SOFT_TISSUE	OR2M5 →	+0.017	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR4X2 →	+0.024	+4.369	<.001	.008	3	1
SOFT_TISSUE	CT83 →	+0.953	+4.635	<.001	.003	3	1
SOFT_TISSUE	PRR20B →	+0.032	+4.977	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

H1-8 by CCNB3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →