CCNB1

Across TCGA patient cohorts, CCNB1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,378 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNB1-associated genes across cancer lineages are CENPM, MCM5, and POLE2. Each is linked with CCNB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCNB1-to-partner and partner-to-CCNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNB1 versus CENPM in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB1→partner) and Y-score (partner→CCNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+1.546	+0.802	<.001	<.001	3	8
UCEC	MCM5 →	+1.229	+0.769	<.001	<.001	3	8
OV	POLE2 →	+0.911	+0.728	<.001	<.001	3	8
OV	CDKN3 →	+1.440	+0.700	<.001	<.001	3	8
HNSC	VRK1 →	+0.769	+0.398	<.001	<.001	3	8
UCEC	CENPI →	+0.979	+0.766	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,378 associations by consensus.

CCNB1 vs CENPM — UCEC

Explore this scatter interactively →