CCNA1

Across TCGA patient cohorts, CCNA1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNA1-associated genes across cancer lineages are GATA6, ASNS, and eEF2. Each is linked with CCNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNA1-to-partner and partner-to-CCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA6 grouped by CCNA1-low versus CCNA1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNA1→partner) and Y-score (partner→CCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GATA6 →	-0.237	-3.321	.011	.010	3	2
COAD	ASNS →	+0.592	+2.178	.001	.035	3	2
UCEC	eEF2 →	+0.302	+1.874	.024	.049	3	2
UCEC	A-Raf_pS299 →	-0.129	-1.765	.004	.014	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.459	+1.415	.016	.046	3	2
UCEC	JNK2 →	+0.204	+1.415	.006	.046	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

GATA6 by CCNA1 expression — COAD

Explore this box plot interactively →