CCNA1

Across TCGA cell cohorts, CCNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,874 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCNA1-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Microtubule cytoskeleton organization involved in mitosis, and Cellular response to type I interferon. Each is linked with CCNA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCNA1-to-partner and partner-to-CCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by CCNA1-low versus CCNA1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNA1→partner) and Y-score (partner→CCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of telomerase RNA localization to Cajal body →	+0.112	+2.703	<.001	<.001	3	10
KIDNEY	Microtubule cytoskeleton organization involved in mitosis →	+0.093	+2.215	<.001	<.001	3	10
SKIN	Cellular response to type I interferon →	+0.085	+0.977	<.001	.002	3	8
OESOPHAGUS	Regulation of translational initiation →	+0.102	+1.895	<.001	.003	3	8
OVARY	Nuclear envelope organization →	+0.056	+1.780	.009	.008	3	8
OVARY	Respiratory electron transport chain →	+0.073	+2.384	.003	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,874 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by CCNA1 expression — OESOPHAGUS

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