CCN3

Across TCGA patient cohorts, CCN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,809 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCN3-associated proteins across cancer lineages are PDLIM7, TIMP2, and CLEC3B. Each is linked with CCN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCN3-to-partner and partner-to-CCN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN3 versus PDLIM7 in UCEC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN3→partner) and Y-score (partner→CCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDLIM7 →	+0.697	+1.125	<.001	<.001	3	6
CCRCC	TIMP2 →	+0.678	+1.261	<.001	<.001	3	6
BRCA	CLEC3B →	+0.686	+1.084	<.001	<.001	3	6
PDAC	ISLR →	+0.781	+0.834	<.001	<.001	3	6
CCRCC	PDLIM4 →	+0.778	+0.986	<.001	.003	3	5
CCRCC	PDLIM5 →	+0.743	+1.055	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,809 associations by consensus.

CCN3 vs PDLIM7 — UCEC

Explore this scatter interactively →