CCN3

Across TCGA patient cohorts, CCN3 mutation is significantly associated with the RNA expression of many other genes, with 543 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCN3-associated genes across cancer lineages are LINC01974, RNU6-505P, and MIR629. Each is linked with CCN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCN3-to-partner and partner-to-CCN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01974 grouped by CCN3-low versus CCN3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN3→partner) and Y-score (partner→CCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC01974 →	+0.096	+4.720	<.001	.005	3	2
LUAD	RNU6-505P →	+0.865	+6.014	<.001	<.001	3	2
HNSC	MIR629 →	+0.440	+5.069	<.001	.008	3	2
LIHC	RNU1-124P →	+0.297	+4.866	<.001	<.001	3	2
LIHC	RNU6-39P →	+0.308	+4.350	<.001	.002	3	2
LIHC	SNRPGP8 →	+0.121	+4.894	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 543 associations by consensus.

LINC01974 by CCN3 expression — LIHC

Explore this box plot interactively →