CCN2

Across TCGA patient cohorts, CCN2 mutation is significantly associated with the RNA expression of many other genes, with 2,955 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCN2-associated genes across cancer lineages are RN7SL248P, RN7SL478P, and DAOA. Each is linked with CCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCN2-to-partner and partner-to-CCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CCN2-low versus CCN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN2→partner) and Y-score (partner→CCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.053	+2.783	<.001	.009	3	2
UCEC	RN7SL478P →	+0.241	+1.676	<.001	.004	3	2
UCEC	DAOA →	+0.055	+1.903	.004	.001	3	2
COAD	RNU6-178P →	+0.937	+4.437	<.001	.002	3	2
LUSC	SLC25A39P2 →	+0.332	+5.739	<.001	<.001	3	2
UCEC	ANP32BP2 →	+0.105	+1.966	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,955 associations by consensus.

RN7SL248P by CCN2 expression — UCEC

Explore this box plot interactively →