CCM2L

Across TCGA pan-cancer cohorts, CCM2L Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCM2L data layer compared with 24 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CCM2L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCM2L expression acts as an unfavorable survival marker.

UCEC, LGG, and COAD are the cancer types where CCM2L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →
LGG	DFS	Median	All	0.132	0.832	<.001	6	view →
COAD	DFS	Median	II,III,IV	0.236	0.654	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCM2L–UCEC (OS)

Open the UCEC breakdown →