CCM2L

Across TCGA patient cohorts, CCM2L protein abundance is significantly associated with the RNA expression of many other genes, with 9,054 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCM2L-associated genes across cancer lineages are FLT1, IKBKB, and TEK. Each is linked with CCM2L in more than 1 cancer types. Because this analysis shows association rather than direction, both CCM2L-to-partner and partner-to-CCM2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCM2L versus FLT1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCM2L→partner) and Y-score (partner→CCM2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FLT1 →	+0.524	+0.389	.002	.008	3	2
LUAD	IKBKB →	-0.655	-0.532	.004	.009	3	2
LUAD	TEK →	+0.864	+0.700	<.001	<.001	3	2
LUAD	LYVE1 →	+1.269	+0.745	<.001	<.001	3	2
LUAD	FAM107A →	+1.217	+0.539	.007	.007	3	2
LUAD	CCDC134 →	-0.320	-0.550	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,054 associations by consensus.

CCM2L vs FLT1 — LSCC

Explore this scatter interactively →