CCL4

Across TCGA cell cohorts, CCL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,560 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCL4-associated GO terms across cancer lineages are Regulation of viral life cycle, Visual perception, and Positive regulation of microglial cell activation. Each is linked with CCL4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCL4-to-partner and partner-to-CCL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of viral life cycle grouped by CCL4-low versus CCL4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL4→partner) and Y-score (partner→CCL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of viral life cycle →	+0.055	+2.072	.002	<.001	3	5
LUNG_NSCLC_LUSC	Visual perception →	-0.042	-0.052	.007	.001	3	5
BLOOD_Lymphoma	Positive regulation of microglial cell activation →	+1.160	+1.904	<.001	<.001	3	4
BLOOD_Leukemia	Regulation of natural killer cell chemotaxis →	+1.138	+1.864	<.001	<.001	3	4
BLOOD_Leukemia	Positive regulation of natural killer cell chemotaxis →	+1.139	+1.826	<.001	<.001	3	4
BLOOD_Myeloma	Pattern recognition receptor signaling pathway →	+0.051	+1.894	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,560 associations by consensus.

Regulation of viral life cycle by CCL4 expression — BLOOD_Myeloma

Explore this box plot interactively →