CCL4

Across TCGA cell cohorts, CCL4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCL4-associated genes across cancer lineages are OR4F4, ELOA3DP, and OR2V1. Each is linked with CCL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL4-to-partner and partner-to-CCL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F4 grouped by CCL4-low versus CCL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL4→partner) and Y-score (partner→CCL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.025	+4.273	<.001	.006	3	1
LARGE_INTESTINE	ELOA3DP →	+0.039	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR4F4 by CCL4 expression — LARGE_INTESTINE

Explore this box plot interactively →