CCL3L3

Across TCGA patient cohorts, CCL3L3 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL3L3-associated genes across cancer lineages are RAC1P8, RNA5SP23, and MIR4689. Each is linked with CCL3L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL3L3-to-partner and partner-to-CCL3L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAC1P8 grouped by CCL3L3-low versus CCL3L3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL3L3→partner) and Y-score (partner→CCL3L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAC1P8 →	+0.059	+7.816	<.001	.008	3	2
SKCM	RNA5SP23 →	+0.263	+7.816	<.001	.008	3	1
UCEC	MIR4689 →	+0.435	+3.548	<.001	.001	3	1
UCEC	SNRPGP17 →	+0.349	+2.463	.001	.008	3	1
UCEC	TNPO3P1 →	+0.069	+3.602	.002	<.001	3	1
UCEC	C17orf98 →	+0.626	+3.298	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

RAC1P8 by CCL3L3 expression — SKCM

Explore this box plot interactively →