CCL3L3

Across TCGA cell cohorts, CCL3L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,126 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCL3L3-associated GO terms across cancer lineages are Positive regulation of interferon-beta production, Glycoprotein catabolic process, and Adaptive immune response. Each is linked with CCL3L3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCL3L3-to-partner and partner-to-CCL3L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of interferon-beta production grouped by CCL3L3-low versus CCL3L3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL3L3→partner) and Y-score (partner→CCL3L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of interferon-beta production →	+0.055	+1.919	<.001	<.001	3	5
KIDNEY	Glycoprotein catabolic process →	+0.092	+0.440	<.001	<.001	3	5
CNS	Adaptive immune response →	+0.046	+0.133	.002	.006	3	4
BLOOD_Lymphoma	Short-term synaptic potentiation →	-0.700	-1.445	.001	.002	3	4
BLOOD_Lymphoma	Regulation of immune complex clearance by monocytes and macrophages →	+1.114	+2.638	<.001	<.001	3	4
BLOOD_Leukemia	Zymogen activation →	+0.115	+1.799	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,126 associations by consensus.

Positive regulation of interferon-beta production by CCL3L3 expression — BLOOD_Leukemia

Explore this box plot interactively →