CCL20

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCL20 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCL20 data layer compared with 26 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCL20 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCL20 expression acts as an unfavorable survival marker.

LUAD and UCEC are the cancer types where CCL20 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.2230.812<.00127view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CCL20–LUAD (OS)

Kaplan–Meier survival curve for CCL20 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration