CCL2

Across TCGA pan-cancer cohorts, CCL2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCL2 data layer compared with 19 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CCL2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCL2 expression acts as an unfavorable survival marker.

LSCC and GBM are the cancer types where CCL2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.922	1.000	.044	2	view →
GBM	DFS	Tertile	All	0.650	0.839	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CCL2–LSCC (DFS)

Open the LSCC breakdown →