CCL2

Across TCGA patient cohorts, CCL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,832 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCL2-associated proteins across cancer lineages are SIPA1, CD163, and ICAM1. Each is linked with CCL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCL2-to-partner and partner-to-CCL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL2 versus SIPA1 in COAD, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL2→partner) and Y-score (partner→CCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SIPA1 →	+0.307	+0.787	<.001	<.001	3	8
GBM	CD163 →	+0.835	+1.631	<.001	<.001	3	8
GBM	ICAM1 →	+0.624	+1.526	<.001	<.001	3	8
GBM	NCF2 →	+0.661	+1.780	<.001	<.001	3	8
OV	CORO1A →	+0.672	+1.479	<.001	<.001	3	7
GBM	DOCK2 →	+0.531	+1.609	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,832 associations by consensus.

CCL2 vs SIPA1 — COAD

Explore this scatter interactively →