CCL2

Across TCGA patient cohorts, CCL2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,853 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCL2-associated genes across cancer lineages are XYLT1, GAPDHP33, and GBE1. Each is linked with CCL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL2-to-partner and partner-to-CCL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL2 versus XYLT1 in UCEC, with a Pearson correlation of -0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL2→partner) and Y-score (partner→CCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	XYLT1 →	-1.179	-1.533	.005	<.001	3	2
GBM	GAPDHP33 →	-0.995	-1.301	.001	.005	3	2
LUAD	GBE1 →	+0.757	+1.333	<.001	.005	3	2
GBM	TGFBI →	+1.566	+1.313	<.001	<.001	3	2
GBM	BHLHE40 →	+1.231	+1.729	<.001	<.001	3	2
GBM	ADM →	+1.541	+1.252	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,853 associations by consensus.

CCL2 vs XYLT1 — UCEC

Explore this scatter interactively →