CCL2

Across TCGA patient cohorts, CCL2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL2-associated genes across cancer lineages are Mesangial cells and Pericytes. Each is linked with CCL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL2-to-partner and partner-to-CCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by CCL2-low versus CCL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL2→partner) and Y-score (partner→CCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.047	-3.153	.026	.019	3	1
UCEC	Pericytes →	+0.044	+2.113	.002	.024	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Mesangial cells by CCL2 expression — UCEC

Explore this box plot interactively →