CCL19

Across TCGA patient cohorts, CCL19 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL19-associated genes across cancer lineages are H4C7, RN7SL478P, and RNU7-107P. Each is linked with CCL19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL19-to-partner and partner-to-CCL19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H4C7 grouped by CCL19-low versus CCL19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL19→partner) and Y-score (partner→CCL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H4C7 →	+0.264	+3.661	.007	.009	3	1
UCEC	RN7SL478P →	+0.495	+4.354	<.001	.002	3	1
SKCM	RNU7-107P →	+0.577	+7.816	<.001	.008	3	1
UCEC	MIR4783 →	+0.505	+4.262	<.001	.003	3	1
SKCM	SNORD114-23 →	+0.513	+7.816	<.001	.008	3	1
SKCM	MIR488 →	+0.623	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

H4C7 by CCL19 expression — UCEC

Explore this box plot interactively →