CCL19

Across TCGA pan-cancer cohorts, CCL19 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCL19’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCL19 RNA is repressed in tumor relative to normal tissue. In most cancer types CCL19 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and UCEC are the cancer types where CCL19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCL19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.638	<.001	9	view →
KICH	All	II,III,IV	−2.477	<.001	9	view →
UCEC	All	All	−2.703	<.001	6	view →
STAD	Female	All	+2.462	.018	4	view →
THCA	All	All	−2.078	<.001	4	view →
BLCA	All	III,IV	−1.999	.019	4	view →
HNSC	Male	II,III,IV	−1.763	<.001	4	view →
KIRP	All	All	−1.655	.003	4	view →
LIHC	All	All	−1.556	<.001	4	view →
LUAD	Female	All	+1.526	<.001	4	view →
READ	All	All	−2.542	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CCL19–COAD

Open the COAD breakdown →