CCL19

Across TCGA cell cohorts, CCL19 RNA expression is significantly associated with the go_rna of many other GO terms, with 194 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CCL19-associated GO terms across cancer lineages are Cellular response to UV-B, Regulation of extrinsic apoptotic signaling pathway, and Platelet aggregation. Each is linked with CCL19 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCL19-to-partner and partner-to-CCL19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to UV-B grouped by CCL19-low versus CCL19-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL19→partner) and Y-score (partner→CCL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular response to UV-B →	+0.103	+0.119	<.001	.008	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of extrinsic apoptotic signaling pathway →	+0.067	+0.042	.001	.004	3	3
BLOOD_Leukemia	Platelet aggregation →	+0.070	+0.121	<.001	.006	3	3
UPPER_AERODIGESTIVE_TRACT	Cellular response to methionine →	+0.049	+0.024	.008	.007	3	2
UPPER_AERODIGESTIVE_TRACT	Glomerular epithelial cell development →	+0.175	+0.039	.005	.002	3	2
UPPER_AERODIGESTIVE_TRACT	Chromosome attachment to the nuclear envelope →	+0.103	+0.024	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

Cellular response to UV-B by CCL19 expression — BLOOD_Leukemia

Explore this box plot interactively →