CCL14

Across TCGA patient cohorts, CCL14 mutation is significantly associated with the RNA expression of many other genes, with 147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL14-associated genes across cancer lineages are MIR3188, MIR8057, and LSM1P2. Each is linked with CCL14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL14-to-partner and partner-to-CCL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3188 grouped by CCL14-low versus CCL14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL14→partner) and Y-score (partner→CCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3188 →	+0.518	+2.743	.001	.001	3	2
SKCM	MIR8057 →	+0.318	+5.212	<.001	.002	3	1
BLCA	LSM1P2 →	+0.129	+7.640	<.001	.009	3	1
UCEC	TRIM73 →	+0.127	+3.480	.005	.002	3	1
UCEC	TMEM150B →	+0.829	+3.470	<.001	.003	3	1
UCEC	HMX2 →	+0.960	+3.416	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 147 associations by consensus.

MIR3188 by CCL14 expression — UCEC

Explore this box plot interactively →