CCL11

Across TCGA patient cohorts, CCL11 mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CCL11-associated genes across cancer lineages are RPS29P32, PHBP15, and RNA5SP402. Each is linked with CCL11 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL11-to-partner and partner-to-CCL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by CCL11-low versus CCL11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL11→partner) and Y-score (partner→CCL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.894	+3.599	<.001	.007	3	2
LUSC	PHBP15 →	+0.105	+5.548	<.001	.004	3	2
UCEC	RNA5SP402 →	+0.666	+3.967	<.001	.001	3	2
LUAD	LINC00709 →	+0.079	+7.930	<.001	.008	3	1
LUAD	RNU7-95P →	+0.411	+7.930	<.001	.008	3	1
UCEC	MIR98 →	+0.519	+3.801	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

RPS29P32 by CCL11 expression — UCEC

Explore this box plot interactively →