CCKAR

Across TCGA patient cohorts, CCKAR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,109 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCKAR-associated GO terms across cancer lineages are Epithelial to mesenchymal transition, Atrioventricular valve development, and Endocardial cushion morphogenesis. Each is linked with CCKAR in more than 18 cancer types. Because this analysis shows association rather than direction, both CCKAR-to-partner and partner-to-CCKAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial to mesenchymal transition grouped by CCKAR-low versus CCKAR-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCKAR→partner) and Y-score (partner→CCKAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Epithelial to mesenchymal transition →	+0.069	+0.675	<.001	<.001	3	17
ESCA	Atrioventricular valve development →	+0.087	+0.370	<.001	<.001	2	18
TGCT	Endocardial cushion morphogenesis →	+0.080	+0.695	<.001	<.001	3	17
ESCA	Regulation of canonical Wnt signaling pathway →	+0.064	+0.235	<.001	<.001	1	19
STAD	Neuron projection extension →	+0.043	+0.587	<.001	<.001	3	17
STAD	Developmental cell growth →	+0.048	+0.581	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,109 associations by consensus.

Epithelial to mesenchymal transition by CCKAR expression — TGCT

Explore this box plot interactively →