CCK

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCK mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CCK-associated genes across cancer lineages are Myocytes, Megakaryocytes, and Platelets. Each is linked with CCK in more than 2 cancer types. Because this analysis shows association rather than direction, both CCK-to-partner and partner-to-CCK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCK→partner) and Y-score (partner→CCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMyocytes →+0.050+3.031.017.01933
SKCMMegakaryocytes →+0.032+2.845.018.03431
COADPlatelets →+0.016+2.624.021.03731
SKCMOsteoblast →-0.043-2.993.042.03711
SKCMpro B-cells →+0.103+3.031.039.01911
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration