Across TCGA pan-cancer cohorts, CCER1 Mutation is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated CCER1 data layer compared with 9 for mass-spec protein.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CCER1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCER1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.
LUSC, UCEC, and COAD are the cancer types where CCER1 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.