CCDC97

Across TCGA cell cohorts, CCDC97 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC97-associated genes across cancer lineages are SIGLEC11, SPACA5, and MYF5. Each is linked with CCDC97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC97-to-partner and partner-to-CCDC97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC11 grouped by CCDC97-low versus CCDC97-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC97→partner) and Y-score (partner→CCDC97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SIGLEC11 →	+0.017	+4.273	.001	.006	3	1
SKIN	SPACA5 →	+0.092	+4.273	<.001	.006	3	1
BREAST	MYF5 →	+0.023	+5.169	<.001	.005	3	1
OVARY	PPY →	+0.255	+4.029	<.001	.009	3	1
BLOOD_Leukemia	CST2 →	+0.353	+4.152	<.001	.009	3	1
BLOOD_Leukemia	EDDM3B →	+0.014	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SIGLEC11 by CCDC97 expression — SKIN

Explore this box plot interactively →