CCDC92B

Across TCGA pan-cancer cohorts, CCDC92B RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CCDC92B’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CCDC92B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC92B is over-expressed in tumor, although a few such as READ and UCEC show the opposite, repressed pattern.

LUSC, READ, and BRCA are the cancer types where CCDC92B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC92B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.171	.002	5	view →
READ	Male	All	−0.263	<.001	4	view →
BRCA	Female	II,III,IV	+0.158	.016	4	view →
UCEC	All	All	−0.148	.039	2	view →
HNSC	All	All	+0.031	.024	2	view →
STAD	Female	III,IV	−0.985	.037	1	view →
COAD	Female	III,IV	−0.166	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CCDC92B–LUSC

Open the LUSC breakdown →