CCDC91

Across TCGA cell cohorts, CCDC91 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC91-associated genes across cancer lineages are ACSM6, OR52H1, and AVPR1B. Each is linked with CCDC91 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC91-to-partner and partner-to-CCDC91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM6 grouped by CCDC91-low versus CCDC91-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC91→partner) and Y-score (partner→CCDC91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACSM6 →	+0.018	+3.144	<.001	.001	3	1
LARGE_INTESTINE	OR52H1 →	+0.024	+3.347	<.001	<.001	3	1
LARGE_INTESTINE	AVPR1B →	+0.020	+2.938	.007	.003	3	1
LARGE_INTESTINE	TAS2R43 →	+0.170	+3.359	<.001	.003	3	1
LARGE_INTESTINE	CCDC195 →	+0.027	+2.560	.009	.008	3	1
LARGE_INTESTINE	PRKCQ →	+0.778	+3.064	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ACSM6 by CCDC91 expression — LARGE_INTESTINE

Explore this box plot interactively →